El día de hoy compartimos una colaboración con Ted-Ed en donde hablamos de los cambios que sufre el cerebro cuando estamos enfermos, en breve se agregarán subtítulos en español. "It starts with a tickle in your throat that becomes a cough. Your muscles begin to ache, you grow irritable, and you lose your appetite. It’s… Sigue leyendo ¿Qué sucede en nuestro cerebro cuando nos sentimos mal? Una colaboración con Ted-Ed.
Continuing with neurotransmitters now we review the main inhibitory neurotransmitter, gamma amino butiric acid a.k.a. GABA, we check out it's physiology and pharmacology. Want to know more about other neurotransmitters? Check this out: The King of Neurotransmitters: Glutamate https://youtu.be/bTXY1G7pm9s
Today we review the physiology and pharmacology of dopamine, it's role in movement, reward and hormone secretion. And check out our video about glutamate: The King of Neurotransmitters: Glutamate https://youtu.be/AtK65kOqQF4
Depression is a terrible disease, according to the WHO approximately 350 million people from all ages has to live with it, it is the leading cause of disability worldwide and in severe cases it leads to suicide. Despite the advances in the field and the availability of a range of antidepressants, still a number of… Sigue leyendo New Frontiers in Depression
The origin of intelligence has been a historical debate, is it acquired or is it inherited? Let us just think about the Bohr family. Christian Bohr was a successful physician in Edinburgh, his son, Niehls Bohr, was a Nobel Laureate in Physics, and his grandson, Aage Bohr also won a Nobel Prize in Physics. So,… Sigue leyendo The origin of intelligence, is it acquired or is it inherited?
Neuronal regeneration occurs naturally in a few restricted mammalian brain regions, but its functional significance remains debated. The vast majority of adult-generated interneurons in the Olfactory Bulb become granule cells. Interestingly, there are several physiological differences between immature granular cells and those that have matured and are stably integrated within the circuit. In fact, previous… Sigue leyendo Different synaptic properties of GABAergic neurons integrated into the Olfactory Bulb during adulthood.
In a recent study, Suter and Sheperd identify many shared features in the circuits of primary motor (M1) and secondary somatosensory (S2) cortices and show that these areas communicate via mutual projections that give each area monosynaptic access to the other one. These interareally corticoespinal (CSPs) neuron circuits may enable M1 and S2 to operate in… Sigue leyendo Understanding sensory-motor circuits, the hierarchical level of the cerebral cortex.
Whereas normal human cells use a process named mitochondrial oxidative phosphorylation (MOP) to generate energy from glucose, some unicellular organisms (eg: microbes) use a different process called anaerobic glycolysis to reproduce as quickly as possible when nutrients are available. The Nobel laureate, Otto Warburg, noticed in 1924 that cancer cells metabolize glucose in a different… Sigue leyendo The cancer therapeutic implications of the Warburg effect.
Inflammation is an immune physiological process that usually helps to control infections as well as in the subsequent repair of the affected tissue. Inflammasomes are multiproteic complexes expressed by the innate immune system cells whose activation induces the release of proinflammatory substances as interleukin-1. These multiproteic complexes are clinically-important because some autoimmune diseases express an… Sigue leyendo Low carb diets. Useful as autoimmune disease treatment?
What is the cause of the pain produced during an infection? Until now it was thought that it is originated by the inflammatory response triggered by immune-derived substances such as cytokines, prostaglandins and growth factors. However, in a recent study published in Nature, researchers from Harvard University found that some peptides in bacteria can directly activate… Sigue leyendo Can bacteria cause pain?